Abstract
This study investigated whether carbohydrate-energy replacement immediately after prolonged endurance exercise attenuates insulin sensitivity the following morning, and whether exercise improves insulin sensitivity the following morning independent of an exercise-induced carbohydrate deficit. Oral glucose tolerance and whole-body insulin sensitivity were compared the morning after 3 evening conditions, involving (1) treadmill exercise followed by a carbohydrate replacement drink (200 or 150 g maltodextrin for males and females, respectively; CHO-replace); (2) treadmill exercise followed by a non-caloric, taste-matched placebo (CHO-deficit); or (3) seated rest with no drink provided (Rest). Treadmill exercise involved 90 minutes at ∼80% age-predicted maximum heart rate. Seven males and 2 females (aged 23 ± 1 years; body mass index 24.0 ± 2.7 kg·m-2) completed all conditions in a randomised order. Matsuda index improved by 22% (2.2 [0.3, 4.0] au, p = 0.03) and HOMA2-IR improved by 10% (-0.04 [-0.08, 0.00] au, p = 0.04) in CHO-deficit versus CHO-replace, without corresponding changes in postprandial glycaemia. Outcomes were similar between Rest and other conditions. These data suggest that improvements to insulin sensitivity in healthy populations following acute moderate/vigorous intensity endurance exercise may be dependent on the presence of a carbohydrate-energy deficit. Novelty: Restoration of carbohydrate balance following acute endurance exercise attenuated whole-body insulin sensitivity. Exercise per se failed to enhance whole-body insulin sensitivity. Maximising or prolonging the post-exercise carbohydrate deficit may enhance acute benefits to insulin sensitivity.
Original language | English |
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Pages (from-to) | 1207 - 1215 |
Number of pages | 9 |
Journal | Applied Physiology Nutrition and Metabolism |
Volume | 46 |
Issue number | 10 |
Early online date | 8 Apr 2021 |
DOIs | |
Publication status | Published - 1 Oct 2021 |
Keywords
- activité physique
- carbohydrate availability
- deficit
- disponibilité en glucides
- déficit
- energy
- glycaemia
- glycaemic
- glycemic
- glycémie
- glycémique
- insulin resistance
- metabolism
- métabolisme
- physical activity
- refeeding
- réalimentation
- résistance à l’insuline
- énergie
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Physiology
- Nutrition and Dietetics
- Physiology (medical)