Realistic simulation of the dynamic effects of walking pedestrians on structures is still a considerable challenge. This is mainly due to the inter- and intrasubject variability of humans and their bodies and difficult-to-predict loading scenarios, including multipedestrian walking traffic and unknown human-structure interaction (HSI) mechanisms. Over the past three decades, several attempts have been made to simulate walking HSI in the lateral direction. However, research into the mechanisms of this interaction in the vertical direction, despite its higher likelihood and critical importance, is fragmented and incoherent. It is, therefore, difficult to apply and codify. This paper critically reviews the efforts to date to simulate walking HSI in the vertical direction and highlights the key areas that need further investigation.