Abstract
A growing share of the pharmaceutical development pipeline is occupied by macromolecule drugs, which are primarily administered by injection. Despite decades of attempts, non-invasive delivery of macromolecules has seen only a few success stories. Potential benefits of non-invasive administration include better patient acceptance and adherence and potentially better efficacy and safety. Greater inter-disciplinary dialogue and collaboration are integral to realizing these benefits.
| Original language | English |
|---|---|
| Pages (from-to) | 1149-1151 |
| Number of pages | 3 |
| Journal | Pharmaceutical Research |
| Volume | 34 |
| Issue number | 6 |
| Early online date | 6 Apr 2017 |
| DOIs |
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| Publication status | Published - 1 Jun 2017 |
Keywords
- blood-brain barrier
- drug delivery
- in vitro models
- macromolecules
- permeation enhancers
ASJC Scopus subject areas
- Biotechnology
- Molecular Medicine
- Pharmacology
- Pharmaceutical Science
- Organic Chemistry
- Pharmacology (medical)