Insights and lessons from a scientific conference on non-invasive delivery of macromolecules

Ronak Savla, Randall J. Mrsny, Kinam Park, Isabelle Aubert, Cornell Stamoran

Research output: Contribution to journalComment/debate

Abstract

A growing share of the pharmaceutical development pipeline is occupied by macromolecule drugs, which are primarily administered by injection. Despite decades of attempts, non-invasive delivery of macromolecules has seen only a few success stories. Potential benefits of non-invasive administration include better patient acceptance and adherence and potentially better efficacy and safety. Greater inter-disciplinary dialogue and collaboration are integral to realizing these benefits.

Original languageEnglish
Pages (from-to)1149-1151
Number of pages3
JournalPharmaceutical Research
Volume34
Issue number6
Early online date6 Apr 2017
DOIs
Publication statusPublished - 1 Jun 2017

Keywords

  • blood-brain barrier
  • drug delivery
  • in vitro models
  • macromolecules
  • permeation enhancers

ASJC Scopus subject areas

  • Biotechnology
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Organic Chemistry
  • Pharmacology (medical)

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