Inhibitory control in psychiatric disorders- a review of neuropsychological and neuroimaging research.

Inhibitory control is an important component of executive function which allows for the suppression of actions and resistance to interference from irrelevant stimuli. Dysfunctional inhibitory control is increasingly being recognised as an important component to a number of neuropsychiatric disorders. This paper reviews neuropsychological and neuroimaging research which documents impaired inhibitory control in Attention Deficit Hyperactivity Disorder, Autism, Tourette’s syndrome, Obsessive-Compulsive Disorder and Schizophrenia, with a focus on different patterns of impaired cognitive and motor inhibition, and related activity in the fronto-striatal circuitry.