Indium triflate catalysed Ene and Friedel Crafts additions to α-imino esters: A one-pot synthesis of α-amino acid derivatives

M. Krakowski, C.G. Frost, J.P. Hartley, K.K. Chauhan

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The indium catalysed additions of electron-rich alkenes and heteroaromatics to an activated α-imino ester is described. The moisture-sensitive substrate is prepared in situ facilitating a convenient synthesis of unnatural α-amino acid derivatives in one-pot from commercially available reagents.
Original languageEnglish
Pages (from-to)228-230
Number of pages3
JournalLetters in Organic Chemistry
Volume3
Issue number3
DOIs
Publication statusPublished - 1 Mar 2006

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