The analytic continuation method has been widely used to phase Bragg reflections from lamellar samples of phospholipids. Here we describe its application to neutron diffraction data, collected from liquid-crystalline (Lα phase) samples of 1,2-dioleoyl-sn-glycero-phosphocholine (DOPC) under a state of shifting lamellar spacing. To provide a comparison with the more normal neutron approach of isotopic substitution using 2H2O, data were collected from similar samples, using the same experimental and optical conditions. We compare the two methods in terms of accuracy of structure factor determination, unambiguity of phase assignment and ease of use.
- Neutron diffraction
- Phase assignment
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Electrical and Electronic Engineering