Impact of Anticholinergic Burden on Cognitive Performance: A Cohort Study of Community-Dwelling Older Adults

Prasad Nishtala, Heather Allore, Ling Han, Hamish Jamieson, Sarah N. Hilmer, Te-Yuan Chyou

Research output: Contribution to journalLetterpeer-review

Abstract

Older people are susceptible to the adverse effects of anticholinergic medications, including cognitive impairment. A systematic review of observational studies reported mixed associations between high anticholinergic burden, a cumulative measure of anticholinergic medications, and cognitive performance in older people. Observational studies may have biased estimates of the impact of exposures, as the exposed and unexposed may systematically differ in covariates associated with the outcomes.
Original languageEnglish
Pages (from-to)1357-1358.e3
JournalJournal of the American Medical Directors Association
Volume21
Issue number9
Early online date10 May 2020
DOIs
Publication statusPublished - Sep 2020

ASJC Scopus subject areas

  • Nursing(all)
  • Health Policy
  • Geriatrics and Gerontology

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