Older people are susceptible to the adverse effects of anticholinergic medications, including cognitive impairment. A systematic review of observational studies reported mixed associations between high anticholinergic burden, a cumulative measure of anticholinergic medications, and cognitive performance in older people. Observational studies may have biased estimates of the impact of exposures, as the exposed and unexposed may systematically differ in covariates associated with the outcomes.
|Journal||Journal of the American Medical Directors Association|
|Early online date||10 May 2020|
|Publication status||Published - Sep 2020|
ASJC Scopus subject areas
- Health Policy
- Geriatrics and Gerontology