TY - JOUR
T1 - Hydrogen peroxide detection in wet air with a Prussian Blue based solid salt bridged three electrode system
AU - Komkova, M.A.
AU - Karyakina, E.E.
AU - Marken, F.
AU - Karyakin, A.A.
PY - 2013/3/5
Y1 - 2013/3/5
N2 - We report on a novel electroanalytical system for hydrogen peroxide (H O) detection in humidity or droplets of aerosol, formed by air bubbling through a washing chamber; the resulting flow mimics the exhaled human breath. The system is based on a planar three-electrode structure (with a Prussian Blue based HO transducer modified working electrode) bridged by a solid salt-saturated filament material (filter paper, cotton textile). Respective to the hydrogen peroxide content in the washing valve, the response of the aerosol-sensing system is linear in the concentration range of 0.1-10 μM, which overlaps the generally accepted H O content in exhaled breath condensate (EBC), with the sensitivity of 8 A M cm. The response to the upper limit of the calibration range is stable for more than 50 injection cycles recorded within 3 days. Both the stability and the suitable calibration range allow one to consider the reported aerosol-sensing system as a prototype for a simple (avoiding intermediate EBC collection) noninvasive diagnostic tool for pulmonary patients.
AB - We report on a novel electroanalytical system for hydrogen peroxide (H O) detection in humidity or droplets of aerosol, formed by air bubbling through a washing chamber; the resulting flow mimics the exhaled human breath. The system is based on a planar three-electrode structure (with a Prussian Blue based HO transducer modified working electrode) bridged by a solid salt-saturated filament material (filter paper, cotton textile). Respective to the hydrogen peroxide content in the washing valve, the response of the aerosol-sensing system is linear in the concentration range of 0.1-10 μM, which overlaps the generally accepted H O content in exhaled breath condensate (EBC), with the sensitivity of 8 A M cm. The response to the upper limit of the calibration range is stable for more than 50 injection cycles recorded within 3 days. Both the stability and the suitable calibration range allow one to consider the reported aerosol-sensing system as a prototype for a simple (avoiding intermediate EBC collection) noninvasive diagnostic tool for pulmonary patients.
UR - http://www.scopus.com/inward/record.url?scp=84874598409&partnerID=8YFLogxK
UR - http://dx.doi.org/10.1021/ac303761h
U2 - 10.1021/ac303761h
DO - 10.1021/ac303761h
M3 - Article
AN - SCOPUS:84874598409
SN - 0003-2700
VL - 85
SP - 2574
EP - 2577
JO - Analytical Chemistry
JF - Analytical Chemistry
IS - 5
ER -