How many different types of femora are there in primary hip osteoarthritis? An active shape modeling study

C. Merle, W. Waldstein, J. S. Gregory, S. R. Goodyear, R. M. Aspden, P. R. Aldinger, D. W. Murray, H. S. Gill

Research output: Contribution to journalArticle

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Abstract

We assessed the variation in proximal femoral canal shape and its association with geometric and demographic parameters in primary hip OA. In a retrospective cohort study, the joint geometry of the proximal femur was evaluated on radiographs and corresponding CT scans of 345 consecutive patients with end-stage hip OA. Active shape modeling (ASM) was performed to assess the variation in endosteal shape of the proximal femur. To identify natural groupings of patients, hierarchical cluster analysis of the shape modes was used. ASM identified 10 independent shape modes accounting for >96% of the variation in proximal femoral canal shape within the dataset. Cluster analysis revealed 10 specific shape clusters. Significant differences in geometric and demographic parameters between the clusters were observed. ASM and subsequent cluster analysis have the potential to identify specific morphological patterns of the proximal femur despite the variability in proximal femoral anatomy. The study identified patterns of proximal femoral canal shape in hip OA that allow a comprehensive classification of variation in shape and its association with joint geometry. Our data may improve future stem designs that will optimize stem fit and simultaneously allow individual restoration of hip biomechanics.
Original languageEnglish
Pages (from-to)413-422
Number of pages10
JournalJournal of Orthopaedic Research
Volume32
Issue number3
Early online date19 Nov 2013
DOIs
Publication statusPublished - 1 Mar 2014

Fingerprint

Hip Osteoarthritis
Thigh
Femur
Hip
Cluster Analysis
Joints
Demography
Biomechanical Phenomena
Anatomy
Cohort Studies
Retrospective Studies

Keywords

  • hip
  • anatomy
  • osteoarthritis
  • shape modeling
  • arthroplasty

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

Cite this

How many different types of femora are there in primary hip osteoarthritis? An active shape modeling study. / Merle, C.; Waldstein, W.; Gregory, J. S.; Goodyear, S. R.; Aspden, R. M.; Aldinger, P. R.; Murray, D. W.; Gill, H. S.

In: Journal of Orthopaedic Research, Vol. 32, No. 3, 01.03.2014, p. 413-422.

Research output: Contribution to journalArticle

Merle, C, Waldstein, W, Gregory, JS, Goodyear, SR, Aspden, RM, Aldinger, PR, Murray, DW & Gill, HS 2014, 'How many different types of femora are there in primary hip osteoarthritis? An active shape modeling study', Journal of Orthopaedic Research, vol. 32, no. 3, pp. 413-422. https://doi.org/10.1002/jor.22518
Merle, C. ; Waldstein, W. ; Gregory, J. S. ; Goodyear, S. R. ; Aspden, R. M. ; Aldinger, P. R. ; Murray, D. W. ; Gill, H. S. / How many different types of femora are there in primary hip osteoarthritis? An active shape modeling study. In: Journal of Orthopaedic Research. 2014 ; Vol. 32, No. 3. pp. 413-422.
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