HLA class II haplotype and autoantibody associations in children with juvenile dermatomyositis and juvenile dermatomyositis-scleroderma overlap

L R Wedderburn, Neil J McHugh, H Chinoy, R G Cooper, F Salway, W E R Ollier, L J McCann, H Varsani, J Dunphy, J North, J E Davidson

Research output: Contribution to journalArticlepeer-review

80 Citations (Scopus)

Abstract

We present clinical data, HLA genotyping and serological profiling on a large cohort of JDM patients and a carefully characterized subset of patients with JDM-SSc overlap. The results confirm known HLA associations and extend the knowledge by stratification of data in serological and clinical subgroups. In the future, a combination of serological and genetic typing may allow for better prediction of clinical course and disease subtype in JDM.
Original languageEnglish
Pages (from-to)1786-1791
Number of pages6
JournalRheumatology
Volume46
Issue number12
DOIs
Publication statusPublished - 2007

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