High volume exercise training in older athletes influences inflammatory and redox responses to acute exercise

André L. Estrela, Aline Zaparte, Jeferson D. Da Silva, José Cláudio Moreira, James E. Turner, Moisés E Bauer

Research output: Contribution to journalArticle

2 Citations (Scopus)
56 Downloads (Pure)

Abstract

To examine whether the volume of previous exercise training in older athletes influences inflammatory, redox, and hormonal profiles, 40 trained marathon runners were divided into higher-volume (HVG, ~480 min/week) and lower-volume groups (LVG, ~240 min/week). Plasma inflammatory proteins, redox biomarkers, salivary testosterone, and cortisol were assessed at restand following two maximal acute exercise bouts. At rest, the LVG exhibited higher CRP, higher protein carbonyls, and lower SOD activity compared to the HVG (p's < .05). In response to exercise, TNF-a declined similarly in both groups whereas CRP increased differentially (+60% LVG; +24% HVG; p's < .05). Protein carbonyls decreased and thiols increased similarly in both groups, but SOD declined differentially between groups (-14% LVG; -20% HVG; p's < .05). Salivary testosterone decreased similarly in both groups, whereas cortisol did not change. A higher volume of training is associated with favorable inflammatory and redox profiles at rest, perhaps mediated by small inflammatory responses to acute exercise.

Original languageEnglish
Pages (from-to)559-569
Number of pages11
JournalJournal of Aging and Physical Activity
Volume25
Issue number4
DOIs
Publication statusPublished - 1 Oct 2017

Fingerprint

Athletes
Oxidation-Reduction
Exercise
Hydrocortisone
Testosterone
Sulfhydryl Compounds
Blood Proteins
Proteins
Biomarkers

Keywords

  • Aging
  • Cortisol
  • Cytokines
  • Exercise training
  • Redox
  • Testosterone

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation
  • Gerontology
  • Geriatrics and Gerontology

Cite this

High volume exercise training in older athletes influences inflammatory and redox responses to acute exercise. / Estrela, André L.; Zaparte, Aline; Da Silva, Jeferson D.; Moreira, José Cláudio; Turner, James E.; Bauer, Moisés E.

In: Journal of Aging and Physical Activity, Vol. 25, No. 4, 01.10.2017, p. 559-569.

Research output: Contribution to journalArticle

Estrela, André L. ; Zaparte, Aline ; Da Silva, Jeferson D. ; Moreira, José Cláudio ; Turner, James E. ; Bauer, Moisés E. / High volume exercise training in older athletes influences inflammatory and redox responses to acute exercise. In: Journal of Aging and Physical Activity. 2017 ; Vol. 25, No. 4. pp. 559-569.
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