High-resolution Isotropic Whole Brain T2 Mapping with Model-based Super-resolution Reconstruction

Wajiha Bano, Gian Franco Piredda, Mike Davies, Ian Marshall, Mohammad Golbabaee, Reto Meuli, Tobias Kober, Jean-philippe Thiran, Tom Hilbert

Research output: Chapter or section in a book/report/conference proceedingChapter in a published conference proceeding


We propose a method to reconstruct 1-mm isotropic T2 maps based on multiple 2D multi-echo spin-echo (MESE) acquisitions. To compensate for the prolonged scan time due to multiple acquisitions, data were highly (10-fold) undersampled. The data was reconstructed by combining a classical super-resolution approach with an iterative model-based reconstruction. The method was tested on a phantom and four healthy
volunteers. T2 values were compared against fully sampled MESE data. The proposed technique allows the assessment of T2 values in brain
structures at high isotropic resolution.
Original languageEnglish
Title of host publicationISMRM 2019
PublisherInternational Society for Magnetic Resonance in Medicine (ISMRM)
Number of pages3
Publication statusPublished - 11 Jun 2018


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