Hedgehog pathway activity downstream of Smoothened is regulated specifically by basal ciliary PKA

Hongyu Zhang; Shujing Chen; Zhuoya Huang; Jin Ben; Yanling Wei; Guangxin Chen; Changxin Wu; Haibo Xie; Zhonghua Zhao; Philip Ingham

Hedgehog pathway activity downstream of Smoothened is regulated specifically by basal ciliary PKA

Hongyu Zhang, Shujing Chen, Zhuoya Huang, Jin Ben, Yanling Wei, Guangxin Chen, Changxin Wu, Haibo Xie, Zhonghua Zhao, Philip Ingham

Department of Life Sciences

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	Cellular & Molecular Biology Letters
Publication status	Acceptance date - 17 Mar 2026

Acknowledgements

We are grateful to Michael Lin, who kindly deposited the AKAR2-CR plasmid used for this study in Addgene, and to Changxin Wu, for providing the high-level experiment platform.

Funding

National Natural Science Foundation of China - 31970738 Central Guidance on Local Science and Technology Development Fund of Shanxi Province - YDZJSX2024D009

Cite this

@article{92507587d59d4fd0b59a46a51848758a,

title = "Hedgehog pathway activity downstream of Smoothened is regulated specifically by basal ciliary PKA",

author = "Hongyu Zhang and Shujing Chen and Zhuoya Huang and Jin Ben and Yanling Wei and Guangxin Chen and Changxin Wu and Haibo Xie and Zhonghua Zhao and Philip Ingham",

year = "2026",

month = mar,

day = "17",

language = "English",

journal = "Cellular \& Molecular Biology Letters",

issn = "1689-1392",

publisher = "Springer Nature",

}

TY - JOUR

T1 - Hedgehog pathway activity downstream of Smoothened is regulated specifically by basal ciliary PKA

AU - Zhang, Hongyu

AU - Chen, Shujing

AU - Huang, Zhuoya

AU - Ben, Jin

AU - Wei, Yanling

AU - Chen, Guangxin

AU - Wu, Changxin

AU - Xie, Haibo

AU - Zhao, Zhonghua

AU - Ingham, Philip

PY - 2026/3/17

Y1 - 2026/3/17

M3 - Article

SN - 1689-1392

JO - Cellular & Molecular Biology Letters

JF - Cellular & Molecular Biology Letters

ER -