Heavier alkaline earth catalyzed ene-yne cyclizations: Atom-efficient access to tetrahydroisoquinoline frameworks

Stephanie Reid, Anthony G M Barrett, Michael S. Hill, Panayiotis A. Procopiou

Research output: Contribution to journalArticle

6 Citations (Scopus)
129 Downloads (Pure)

Abstract

Tetrahydroisoquinoline frameworks may be accessed with 100% atom efficiency through the alkaline earth catalyzed addition of primary amines to ene-yne substrates through a sequence of intermolecular alkene and intramolecular alkyne hydroamination steps.

Original languageEnglish
Pages (from-to)6016-6019
Number of pages4
JournalOrganic Letters
Volume16
Issue number22
Early online date10 Nov 2014
DOIs
Publication statusPublished - 21 Nov 2014

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