H-Comb nanodevices for the study of intracellular forces and mechanical property changes in one-cell embryo development

Marta Duch; Nuria Torras; Maki Asami; Maria Isabel Arjona; Matthew  Vermilyea; Robert Castilla; Jose A Plaza; Anthony Perry

H-Comb nanodevices for the study of intracellular forces and mechanical property changes in one-cell embryo development

Marta Duch, Nuria Torras, Maki Asami, Maria Isabel Arjona, Matthew Vermilyea, Robert Castilla, Jose A Plaza, Anthony Perry

Department of Life Sciences

Research output: Contribution to conference › Abstract

Abstract

Intracellular mechanics is a key determinant of cell biology. However, intracellular mechanics are difficult to study in a direct way. Intracellular silicon-based nanodevices open up opportunities to analyze intracellular mechanobiology. A mass production and high reproducility H-comb mechanical sensor microinjected together with the sperm head in an II oocyte allows tracking and quantifying a program of intracellular forces and mechanical properties changes during the first stages of the one-cell mouse embryo, from fertilization to first division. It has been also demonstrated the need of this corresponding fo

Original language	English
Publication status	Published - 19 Sep 2022
Event	48th international conference on Micro and Nano Engineering - Eurosensors (MNE-ES) - Duration: 19 Sep 2022 → …

Conference

Conference	48th international conference on Micro and Nano Engineering - Eurosensors (MNE-ES)
Period	19/09/22 → …

Cite this

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title = "H-Comb nanodevices for the study of intracellular forces and mechanical property changes in one-cell embryo development",

abstract = "Intracellular mechanics is a key determinant of cell biology. However, intracellular mechanics are difficult to study in a direct way. Intracellular silicon-based nanodevices open up opportunities to analyze intracellular mechanobiology. A mass production and high reproducility H-comb mechanical sensor microinjected together with the sperm head in an II oocyte allows tracking and quantifying a program of intracellular forces and mechanical properties changes during the first stages of the one-cell mouse embryo, from fertilization to first division. It has been also demonstrated the need of this corresponding fo",

author = "Marta Duch and Nuria Torras and Maki Asami and Arjona, {Maria Isabel} and Matthew Vermilyea and Robert Castilla and Plaza, {Jose A} and Anthony Perry",

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note = "48th international conference on Micro and Nano Engineering - Eurosensors (MNE-ES) ; Conference date: 19-09-2022",

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TY - CONF

T1 - H-Comb nanodevices for the study of intracellular forces and mechanical property changes in one-cell embryo development

AU - Duch, Marta

AU - Torras, Nuria

AU - Asami, Maki

AU - Arjona, Maria Isabel

AU - Vermilyea, Matthew

AU - Castilla, Robert

AU - Plaza, Jose A

AU - Perry, Anthony

PY - 2022/9/19

Y1 - 2022/9/19

N2 - Intracellular mechanics is a key determinant of cell biology. However, intracellular mechanics are difficult to study in a direct way. Intracellular silicon-based nanodevices open up opportunities to analyze intracellular mechanobiology. A mass production and high reproducility H-comb mechanical sensor microinjected together with the sperm head in an II oocyte allows tracking and quantifying a program of intracellular forces and mechanical properties changes during the first stages of the one-cell mouse embryo, from fertilization to first division. It has been also demonstrated the need of this corresponding fo

AB - Intracellular mechanics is a key determinant of cell biology. However, intracellular mechanics are difficult to study in a direct way. Intracellular silicon-based nanodevices open up opportunities to analyze intracellular mechanobiology. A mass production and high reproducility H-comb mechanical sensor microinjected together with the sperm head in an II oocyte allows tracking and quantifying a program of intracellular forces and mechanical properties changes during the first stages of the one-cell mouse embryo, from fertilization to first division. It has been also demonstrated the need of this corresponding fo

M3 - Abstract

T2 - 48th international conference on Micro and Nano Engineering - Eurosensors (MNE-ES)

Y2 - 19 September 2022

ER -

H-Comb nanodevices for the study of intracellular forces and mechanical property changes in one-cell embryo development

Abstract

Conference

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