Glycosylation enhances the aqueous sensitivity and lowers the cytotoxicity of a naphthalimide zinc ion fluorescence probe

Lei Dong, Yi Zang, Dan Zhou, Xiao Peng He, Guo Rong Chen, Tony D. James, Jia Li

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

With this research we demonstrate that glycosylation of a naphthalimide zinc ion probe, using click chemistry, leads to an improvement of the aqueous sensitivity, working pH range and targeting ability for specific cells, together with significantly reduced cytotoxicity.

Original languageEnglish
Pages (from-to)11852-11855
Number of pages4
JournalChemical Communications
Volume51
Issue number59
Early online date18 Jun 2015
DOIs
Publication statusPublished - 28 Jul 2015

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