Aggregates of an amphiphilic monoboronic acid bearing a hydrophobic pyrene fluorophore were employed for highly modulating, sensitive, and selective ratiometric fluorescent sensing of glucose in aqueous solution. The selectivity for glucose was improved by “knock-out” binding of fructose by phenylboronic acid.
Huang, Y-J., Ouyang, W-J., Wu, X., Li, Z., Fossey, J. S., James, T. D., & Jiang, Y-B. (2013). Glucose sensing via aggregation and the use of “knock-out” binding to improve selectivity. Journal of the American Chemical Society, 135(5), 1700-1703. https://doi.org/10.1021/ja311442x