Glucose sensing via aggregation and the use of “knock-out” binding to improve selectivity

Yan-Jun Huang; Wen-Juan Ouyang; Xin Wu; Zhao Li; John S. Fossey; Tony D. James; Yun-Bao Jiang

doi:10.1021/ja311442x

Glucose sensing via aggregation and the use of “knock-out” binding to improve selectivity

Yan-Jun Huang, Wen-Juan Ouyang, Xin Wu, Zhao Li, John S. Fossey, Tony D. James, Yun-Bao Jiang

Research output: Contribution to journal › Article › peer-review

182 Citations (SciVal)

Abstract

Aggregates of an amphiphilic monoboronic acid bearing a hydrophobic pyrene fluorophore were employed for highly modulating, sensitive, and selective ratiometric fluorescent sensing of glucose in aqueous solution. The selectivity for glucose was improved by “knock-out” binding of fructose by phenylboronic acid.

Original language	English
Pages (from-to)	1700-1703
Number of pages	4
Journal	Journal of the American Chemical Society
Volume	135
Issue number	5
Early online date	14 Jan 2013
DOIs	https://doi.org/10.1021/ja311442x
Publication status	Published - 6 Feb 2013

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10.1021/ja311442x

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abstract = "Aggregates of an amphiphilic monoboronic acid bearing a hydrophobic pyrene fluorophore were employed for highly modulating, sensitive, and selective ratiometric fluorescent sensing of glucose in aqueous solution. The selectivity for glucose was improved by “knock-out” binding of fructose by phenylboronic acid.",

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AU - Li, Zhao

AU - Fossey, John S.

AU - James, Tony D.

AU - Jiang, Yun-Bao

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AB - Aggregates of an amphiphilic monoboronic acid bearing a hydrophobic pyrene fluorophore were employed for highly modulating, sensitive, and selective ratiometric fluorescent sensing of glucose in aqueous solution. The selectivity for glucose was improved by “knock-out” binding of fructose by phenylboronic acid.

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Glucose sensing via aggregation and the use of “knock-out” binding to improve selectivity

Abstract

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