Glucocorticoid ultradian rhythms

Research output: Contribution to journalReview articlepeer-review

Abstract

Ultradian glucocorticoid rhythms are highly conserved across mammalian species and robustly oscillate within a cyclical dynamic signalling network. Despite this, the role of ultradian signalling and the effects of its dysregulation for cognitive processing and metabolic homeostasis is often overlooked within chrono-biological research. This review will discuss ultradian specific signalling and transcriptional mechanisms and the proposed models and repercussion of ultradian dysregulation for cognitive and metabolic function. Highlighting emerging therapeutic treatment that may have significant impacts for future patient care and treatment.
Original languageEnglish
Article number100362
JournalCurrent Opinion in Endocrine and Metabolic Research
Volume25
Early online date30 May 2022
DOIs
Publication statusPublished - 25 Aug 2022

Keywords

  • Glucocorticoid receptor
  • Hypercortisolism
  • Metabolic syndrome
  • Mineralocorticoid receptor
  • Stress
  • Ultradian

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism

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