Fragment-based design for the development of N-domain-selective angiotensin-1-converting enzyme inhibitors

Ross G. Douglas; Rajni K. Sharma; Geoffrey Masuyer; Lizelle Lubbe; Ismael Zamora; K Ravi Acharya; Kelly Chibale; Edward D. Sturrock

doi:10.1042/CS20130403

Fragment-based design for the development of N-domain-selective angiotensin-1-converting enzyme inhibitors

Ross G. Douglas
, Rajni K. Sharma
, Geoffrey Masuyer
, Lizelle Lubbe
, Ismael Zamora
, K Ravi Acharya
, Kelly Chibale
, Edward D. Sturrock

Department of Life Sciences

University of Cape Town
Lead Molecular Design S.L.
Universitat Pompeu Fabra

Research output: Contribution to journal › Article › peer-review

45 Citations (SciVal)

Original language	English
Pages (from-to)	305-313
Journal	Clinical Science
Volume	126
Issue number	4
DOIs	https://doi.org/10.1042/CS20130403
Publication status	Published - 1 Feb 2014

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10.1042/CS20130403

Cite this

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title = "Fragment-based design for the development of N-domain-selective angiotensin-1-converting enzyme inhibitors",

author = "Ross G. Douglas and Rajni K. Sharma and Geoffrey Masuyer and Lizelle Lubbe and Ismael Zamora and Acharya, \{K Ravi\} and Kelly Chibale and Edward D. Sturrock",

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doi = "10.1042/CS20130403",

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journal = "Clinical Science",

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AU - Douglas, Ross G.

AU - Sharma, Rajni K.

AU - Masuyer, Geoffrey

AU - Lubbe, Lizelle

AU - Zamora, Ismael

AU - Acharya, K Ravi

AU - Chibale, Kelly

AU - Sturrock, Edward D.

PY - 2014/2/1

Y1 - 2014/2/1

UR - https://www.scopus.com/pages/publications/84886673811

UR - http://dx.doi.org/10.1042/CS20130403

U2 - 10.1042/CS20130403

DO - 10.1042/CS20130403

M3 - Article

SN - 0143-5221

VL - 126

SP - 305

EP - 313

JO - Clinical Science

JF - Clinical Science

IS - 4

ER -

Fragment-based design for the development of N-domain-selective angiotensin-1-converting enzyme inhibitors

Access to Document

Other files and links

Structural Studies on Human Angiotensin-1 Converting Enzyme (ACE) and the Design of Novel Domain-Specific Inhibitors

MC2- Nuclear Magnetic Resonance (NMR)

Cite this

Fragment-based design for the development of N-domain-selective angiotensin-1-converting enzyme inhibitors

Access to Document

Other files and links

Projects

Structural Studies on Human Angiotensin-1 Converting Enzyme (ACE) and the Design of Novel Domain-Specific Inhibitors

Equipment

MC2- Nuclear Magnetic Resonance (NMR)

Cite this