Four new jacaranone analogs from the fruits of a Beibu Gulf mangrove Avicennia marina

Xiang -Xi Yi; Yong Chen; Wen-Pei Xie; Ming-Ben Xu; Yin-Ning Chen; Cheng-Hai Gao; Ri-Ming Huang

doi:10.3390/md12052515

Four new jacaranone analogs from the fruits of a Beibu Gulf mangrove Avicennia marina

Xiang -Xi Yi, Yong Chen, Wen-Pei Xie, Ming-Ben Xu, Yin-Ning Chen, Cheng-Hai Gao, Ri-Ming Huang

Department of Life Sciences

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Abstract

Four new jacaranone analogs, marinoids F-I (1-4), were isolated from the fruits of a Beibu Gulf mangrove Avicennia marina. The structures were elucidated based on analysis of spectroscopic data. Marinoids F and G are shown to be diastereoisomers of chlorocornoside, a new halogen containing marine secondary metabolite. The antioxidant activity of the isolates was evaluated using a cellular antioxidant assay, and 4 showed good antioxidant activity (EC₅₀ = 26 μM).

Original language	English
Pages (from-to)	2515-2525
Number of pages	11
Journal	Marine Drugs
Volume	12
Issue number	5
DOIs	https://doi.org/10.3390/md12052515
Publication status	Published - 30 Apr 2014

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abstract = "Four new jacaranone analogs, marinoids F-I (1-4), were isolated from the fruits of a Beibu Gulf mangrove Avicennia marina. The structures were elucidated based on analysis of spectroscopic data. Marinoids F and G are shown to be diastereoisomers of chlorocornoside, a new halogen containing marine secondary metabolite. The antioxidant activity of the isolates was evaluated using a cellular antioxidant assay, and 4 showed good antioxidant activity (EC50 = 26 μM).",

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AU - Yi, Xiang -Xi

AU - Chen, Yong

AU - Xie, Wen-Pei

AU - Xu, Ming-Ben

AU - Chen, Yin-Ning

AU - Gao, Cheng-Hai

AU - Huang, Ri-Ming

PY - 2014/4/30

Y1 - 2014/4/30

N2 - Four new jacaranone analogs, marinoids F-I (1-4), were isolated from the fruits of a Beibu Gulf mangrove Avicennia marina. The structures were elucidated based on analysis of spectroscopic data. Marinoids F and G are shown to be diastereoisomers of chlorocornoside, a new halogen containing marine secondary metabolite. The antioxidant activity of the isolates was evaluated using a cellular antioxidant assay, and 4 showed good antioxidant activity (EC50 = 26 μM).

AB - Four new jacaranone analogs, marinoids F-I (1-4), were isolated from the fruits of a Beibu Gulf mangrove Avicennia marina. The structures were elucidated based on analysis of spectroscopic data. Marinoids F and G are shown to be diastereoisomers of chlorocornoside, a new halogen containing marine secondary metabolite. The antioxidant activity of the isolates was evaluated using a cellular antioxidant assay, and 4 showed good antioxidant activity (EC50 = 26 μM).

UR - http://dx.doi.org/10.3390/md12052515

UR - http://www.scopus.com/inward/record.url?scp=84901402071&partnerID=8YFLogxK

UR - https://www.scopus.com/pages/publications/84901402071

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SN - 1660-3397

VL - 12

SP - 2515

EP - 2525

JO - Marine Drugs

JF - Marine Drugs

IS - 5

ER -

Four new jacaranone analogs from the fruits of a Beibu Gulf mangrove Avicennia marina

Abstract

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