Fiber four-wave mixing source for coherent anti-Stokes Raman scattering microscopy

Simon Lefrancois, Dan Fu, Gary R. Holtom, Lingjie Kong, William J. Wadsworth, Patrick Schneider, Robert Herda, Armin Zach, X. Sunney Xie, Frank W. Wise

Research output: Contribution to journalArticlepeer-review

77 Citations (Scopus)
409 Downloads (Pure)

Abstract

We present a fiber-format picosecond light source for coherent anti-Stokes Raman scattering microscopy. Pulses from a Yb-doped fiber amplifier are frequency converted by four-wave mixing (FWM) in normal-dispersion photonic crystal fiber to produce a synchronized two-color picosecond pulse train. We show that seeding the FWM process overcomes the deleterious effects of group-velocity mismatch and allows efficient conversion into narrow frequency bands. The source generates more than 160 mW of nearly transform-limited pulses tunable from 775 to 815 nm. High-quality coherent Raman images of animal tissues and cells acquired with this source are presented.
Original languageEnglish
Pages (from-to)1652-1654
JournalOptics Letters
Volume37
Issue number10
DOIs
Publication statusPublished - 15 May 2012

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