Projects per year
The interaction of ferrocene-boronic acid with fructose is investigated in aqueous 0.1 M phosphate buffer at pH 7, 8 and 9. Two voltammetric methods, based on 1) a dual-plate generator–collector micro-trench electrode (steady state) and 2) a square-wave voltammetry (transient) method, are applied and compared in terms of mechanistic resolution. A combination of experimental data is employed to obtain new insights into the binding rates and the cumulative binding constants for both the reduced ferrocene-boronic acid (pH dependent and weakly binding) and for the oxidised ferrocene-boronic acid (pH independent and strongly binding).
Li, M., Xu, S-Y., Gross, A., Hammond, J., Estrela, P., Weber, J., Lacina, K., James, T., & Marken, F. (2015). Ferrocene-boronic acid–fructose binding based on dual-plate generator–collector voltammetry and square-wave voltammetry. ChemElectroChem, 2(6), 867-871. https://doi.org/10.1002/celc.201500016