Facile Synthesis of Novel Hybrid POSS Biomolecules via “Click” Reaction

Y El Aziz; N Mehrban; PG Taylor; MA Birchall; J Bowen; AR Bassindale; MB Pitak; SJ Cole

doi:10.1039/C7RA07915J

Facile Synthesis of Novel Hybrid POSS Biomolecules via “Click” Reaction

Y El Aziz, N Mehrban, PG Taylor, MA Birchall, J Bowen, AR Bassindale, MB Pitak, SJ Cole

Research output: Contribution to journal › Article › peer-review

7 Citations (SciVal)

Abstract

A novel alkyne-terminated cubic-octameric POSS was synthesised in high yield (82–90%). The X-ray crystal structure revealed intra- and intermolecular hydrogen bonding between the amide groups of the arms. Hybrid biomaterials were synthesised in nearly quantitative yields via a click reaction with (i) azido-N-Fmoc-norleucine and (ii) 3′-azido-3′-deoxythymidine.

Original language	English
Pages (from-to)	37474-37477
Journal	RSC Advances
Volume	7
DOIs	https://doi.org/10.1039/C7RA07915J
Publication status	Published - 21 Jul 2017
Externally published	Yes

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10.1039/C7RA07915JLicence: CC BY

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title = "Facile Synthesis of Novel Hybrid POSS Biomolecules via “Click” Reaction",

abstract = "A novel alkyne-terminated cubic-octameric POSS was synthesised in high yield (82–90\%). The X-ray crystal structure revealed intra- and intermolecular hydrogen bonding between the amide groups of the arms. Hybrid biomaterials were synthesised in nearly quantitative yields via a click reaction with (i) azido-N-Fmoc-norleucine and (ii) 3′-azido-3′-deoxythymidine.",

author = "\{El Aziz\}, Y and N Mehrban and PG Taylor and MA Birchall and J Bowen and AR Bassindale and MB Pitak and SJ Cole",

year = "2017",

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T1 - Facile Synthesis of Novel Hybrid POSS Biomolecules via “Click” Reaction

AU - El Aziz, Y

AU - Mehrban, N

AU - Taylor, PG

AU - Birchall, MA

AU - Bowen, J

AU - Bassindale, AR

AU - Pitak, MB

AU - Cole, SJ

PY - 2017/7/21

Y1 - 2017/7/21

N2 - A novel alkyne-terminated cubic-octameric POSS was synthesised in high yield (82–90%). The X-ray crystal structure revealed intra- and intermolecular hydrogen bonding between the amide groups of the arms. Hybrid biomaterials were synthesised in nearly quantitative yields via a click reaction with (i) azido-N-Fmoc-norleucine and (ii) 3′-azido-3′-deoxythymidine.

AB - A novel alkyne-terminated cubic-octameric POSS was synthesised in high yield (82–90%). The X-ray crystal structure revealed intra- and intermolecular hydrogen bonding between the amide groups of the arms. Hybrid biomaterials were synthesised in nearly quantitative yields via a click reaction with (i) azido-N-Fmoc-norleucine and (ii) 3′-azido-3′-deoxythymidine.

UR - https://www.scopus.com/pages/publications/85026751045

U2 - 10.1039/C7RA07915J

DO - 10.1039/C7RA07915J

M3 - Article

SN - 2046-2069

VL - 7

SP - 37474

EP - 37477

JO - RSC Advances

JF - RSC Advances

ER -

Facile Synthesis of Novel Hybrid POSS Biomolecules via “Click” Reaction

Abstract

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