Facile Synthesis of Novel Hybrid POSS Biomolecules via “Click” Reaction

Y El Aziz, N Mehrban, PG Taylor, MA Birchall, J Bowen, AR Bassindale, MB Pitak, SJ Cole

Research output: Contribution to journalArticlepeer-review

5 Citations (SciVal)


A novel alkyne-terminated cubic-octameric POSS was synthesised in high yield (82–90%). The X-ray crystal structure revealed intra- and intermolecular hydrogen bonding between the amide groups of the arms. Hybrid biomaterials were synthesised in nearly quantitative yields via a click reaction with (i) azido-N-Fmoc-norleucine and (ii) 3′-azido-3′-deoxythymidine.
Original languageEnglish
Pages (from-to)37474-37477
JournalRSC Advances
Publication statusPublished - 21 Jul 2017
Externally publishedYes


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