TY - JOUR
T1 - Fabrication of BioFET Linear Array for Detection of Protein Interactions
AU - Wang, L
AU - Estrela, Pedro
AU - Huq, E
AU - Li, P
AU - Thomas, S
AU - Ko Ferrigno, P
AU - Paul, D
AU - Adkin, P
AU - Migliorato, P
N1 - The 35th International Conference on Micro- and Nano-Engineering (MNE), The 35th International Conference on Micro- and Nano-Engineering (MNE)
PY - 2010/5
Y1 - 2010/5
N2 - An extended-gate MOSFETs (metal–oxide-semiconductor field-effect transistors) based biosensing linear array has been fabricated for label-free protein interaction detection. The device was realized using a combination of very low leakage current MOSFET transistors and an external gate where the chemical reaction would take place. Peptide aptamers that recognize cyclin-dependent kinase (CDK), a protein cancer marker, were used as a biological test system. The test results showed a high sensitive in the detection of CDK.
AB - An extended-gate MOSFETs (metal–oxide-semiconductor field-effect transistors) based biosensing linear array has been fabricated for label-free protein interaction detection. The device was realized using a combination of very low leakage current MOSFET transistors and an external gate where the chemical reaction would take place. Peptide aptamers that recognize cyclin-dependent kinase (CDK), a protein cancer marker, were used as a biological test system. The test results showed a high sensitive in the detection of CDK.
UR - http://www.scopus.com/inward/record.url?scp=76949100384&partnerID=8YFLogxK
UR - http://dx.doi.org/10.1016/j.mee.2009.11.148
U2 - 10.1016/j.mee.2009.11.148
DO - 10.1016/j.mee.2009.11.148
M3 - Article
SN - 0167-9317
VL - 87
SP - 753
EP - 755
JO - Microelectronic Engineering
JF - Microelectronic Engineering
IS - 5-8
T2 - 35th International Conference on Micro & Nano Engineering (MNE)
Y2 - 28 September 2009 through 1 October 2009
ER -
