An extended-gate MOSFETs (metal–oxide-semiconductor field-effect transistors) based biosensing linear array has been fabricated for label-free protein interaction detection. The device was realized using a combination of very low leakage current MOSFET transistors and an external gate where the chemical reaction would take place. Peptide aptamers that recognize cyclin-dependent kinase (CDK), a protein cancer marker, were used as a biological test system. The test results showed a high sensitive in the detection of CDK.
|Number of pages||3|
|Publication status||Published - May 2010|
|Event||35th International Conference on Micro & Nano Engineering (MNE) - Ghent, Belgium|
Duration: 28 Sep 2009 → 1 Oct 2009