Fabrication of a label-free micromechanical capacitive biosensor and integration with μPCR towards a LoC for disease diagnosis

Despina Moschou; Nikolaos Vourdas; George Kokkoris; George Tsekenis; Vasiliki Tsouti; Ioanna Zergioti; Angeliki Tserepi; Stavros Chatzandroulis

Fabrication of a label-free micromechanical capacitive biosensor and integration with μPCR towards a LoC for disease diagnosis

Despina Moschou, Nikolaos Vourdas, George Kokkoris, George Tsekenis, Vasiliki Tsouti, Ioanna Zergioti, Angeliki Tserepi, Stavros Chatzandroulis

Department of Electronic & Electrical Engineering

Research output: Chapter or section in a book/report/conference proceeding › Chapter in a published conference proceeding

2 Citations (SciVal)

Abstract

A label-free micromechanical, capacitive type, biosensor is presented and evaluated. The sensor is integrated together with a continuous flow μPCR on a common printed circuit board (PCB) platform. In this scheme, the sensor is placed into a cavity formed on the PCB to provide the hybridization chamber, while the μPCR channel is implemented in thin photo-patternable polyimide films to maintain biocompatibility, and lies directly on top of the microheaters formed on the PCB Cu layer to provide the three thermal zones necessary for PCR.

Original language	English
Title of host publication	Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), 2012
Publisher	Chemical and Biological Microsystems Society
Pages	1804-1806
Number of pages	3
ISBN (Print)	9780979806452
Publication status	Published - 2012
Event	16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 - Okinawa, Japan Duration: 28 Oct 2012 → 1 Nov 2012

Conference

Conference	16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
Country/Territory	Japan
City	Okinawa
Period	28/10/12 → 1/11/12

Keywords

Capacitive biosensors
Lab-on-chip
Microfluidics
μPCR
μTAS

Cite this

Moschou, D., Vourdas, N., Kokkoris, G., Tsekenis, G., Tsouti, V., Zergioti, I., Tserepi, A., & Chatzandroulis, S. (2012). Fabrication of a label-free micromechanical capacitive biosensor and integration with μPCR towards a LoC for disease diagnosis. In Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), 2012 (pp. 1804-1806). Chemical and Biological Microsystems Society.

Fabrication of a label-free micromechanical capacitive biosensor and integration with μPCR towards a LoC for disease diagnosis. / Moschou, Despina; Vourdas, Nikolaos; Kokkoris, George et al.
Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), 2012. Chemical and Biological Microsystems Society, 2012. p. 1804-1806.

Research output: Chapter or section in a book/report/conference proceeding › Chapter in a published conference proceeding

Moschou, D, Vourdas, N, Kokkoris, G, Tsekenis, G, Tsouti, V, Zergioti, I, Tserepi, A & Chatzandroulis, S 2012, Fabrication of a label-free micromechanical capacitive biosensor and integration with μPCR towards a LoC for disease diagnosis. in Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), 2012. Chemical and Biological Microsystems Society, pp. 1804-1806, 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012, Okinawa, Japan, 28/10/12.

Moschou D, Vourdas N, Kokkoris G, Tsekenis G, Tsouti V, Zergioti I et al. Fabrication of a label-free micromechanical capacitive biosensor and integration with μPCR towards a LoC for disease diagnosis. In Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), 2012. Chemical and Biological Microsystems Society. 2012. p. 1804-1806

Moschou, Despina ; Vourdas, Nikolaos ; Kokkoris, George et al. / Fabrication of a label-free micromechanical capacitive biosensor and integration with μPCR towards a LoC for disease diagnosis. Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), 2012. Chemical and Biological Microsystems Society, 2012. pp. 1804-1806

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abstract = "A label-free micromechanical, capacitive type, biosensor is presented and evaluated. The sensor is integrated together with a continuous flow μPCR on a common printed circuit board (PCB) platform. In this scheme, the sensor is placed into a cavity formed on the PCB to provide the hybridization chamber, while the μPCR channel is implemented in thin photo-patternable polyimide films to maintain biocompatibility, and lies directly on top of the microheaters formed on the PCB Cu layer to provide the three thermal zones necessary for PCR.",

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Fabrication of a label-free micromechanical capacitive biosensor and integration with μPCR towards a LoC for disease diagnosis

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