Fabrication of a label-free micromechanical capacitive biosensor and integration with μPCR towards a LoC for disease diagnosis

Despina Moschou, Nikolaos Vourdas, George Kokkoris, George Tsekenis, Vasiliki Tsouti, Ioanna Zergioti, Angeliki Tserepi, Stavros Chatzandroulis

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

A label-free micromechanical, capacitive type, biosensor is presented and evaluated. The sensor is integrated together with a continuous flow μPCR on a common printed circuit board (PCB) platform. In this scheme, the sensor is placed into a cavity formed on the PCB to provide the hybridization chamber, while the μPCR channel is implemented in thin photo-patternable polyimide films to maintain biocompatibility, and lies directly on top of the microheaters formed on the PCB Cu layer to provide the three thermal zones necessary for PCR.

Original languageEnglish
Title of host publicationProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), 2012
PublisherChemical and Biological Microsystems Society
Pages1804-1806
Number of pages3
ISBN (Print)9780979806452
Publication statusPublished - 2012
Event16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 - Okinawa, Japan
Duration: 28 Oct 20121 Nov 2012

Conference

Conference16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
CountryJapan
CityOkinawa
Period28/10/121/11/12

Keywords

  • Capacitive biosensors
  • Lab-on-chip
  • Microfluidics
  • μPCR
  • μTAS

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