Exploring Tandem Ruthenium-Catalyzed Hydrogen Transfer and SNAr Chemistry

Kurt Polidano; Benjamin G. Reed-Berendt; Anaïs Basset; Andrew J.A. Watson; Jonathan M.J. Williams; Louis C. Morrill

doi:10.1021/acs.orglett.7b03441

Exploring Tandem Ruthenium-Catalyzed Hydrogen Transfer and S_NAr Chemistry

Kurt Polidano, Benjamin G. Reed-Berendt, Anaïs Basset, Andrew J.A. Watson, Jonathan M.J. Williams, Louis C. Morrill

Department of Chemistry

Cardiff University

Research output: Contribution to journal › Article › peer-review

9 Citations (SciVal)

Abstract

A hydrogen-transfer strategy for the catalytic functionalization of benzylic alcohols via electronic arene activation, accessing a diverse range of bespoke diaryl ethers and aryl amines in excellent isolated yields (38 examples, 70% average yield), is reported. Taking advantage of the hydrogen-transfer approach, the oxidation level of the functionalized products can be selected by judicious choice of simple and inexpensive additives.

Original language	English
Pages (from-to)	6716-6719
Number of pages	4
Journal	Organic Letters
Volume	19
Issue number	24
DOIs	https://doi.org/10.1021/acs.orglett.7b03441
Publication status	Published - 15 Dec 2017

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/acs.orglett.7b03441

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abstract = "A hydrogen-transfer strategy for the catalytic functionalization of benzylic alcohols via electronic arene activation, accessing a diverse range of bespoke diaryl ethers and aryl amines in excellent isolated yields (38 examples, 70% average yield), is reported. Taking advantage of the hydrogen-transfer approach, the oxidation level of the functionalized products can be selected by judicious choice of simple and inexpensive additives.",

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AU - Basset, Anaïs

AU - Watson, Andrew J.A.

AU - Williams, Jonathan M.J.

AU - Morrill, Louis C.

PY - 2017/12/15

Y1 - 2017/12/15

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AB - A hydrogen-transfer strategy for the catalytic functionalization of benzylic alcohols via electronic arene activation, accessing a diverse range of bespoke diaryl ethers and aryl amines in excellent isolated yields (38 examples, 70% average yield), is reported. Taking advantage of the hydrogen-transfer approach, the oxidation level of the functionalized products can be selected by judicious choice of simple and inexpensive additives.

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M3 - Article

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Exploring Tandem Ruthenium-Catalyzed Hydrogen Transfer and S_NAr Chemistry

Abstract

ASJC Scopus subject areas

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