Experience-dependent modification of mechanisms of long-term depression.

J Jo; S M Ball; H Seok; S B Oh; Peter V Massey; E Molnar; Z I Bashir; K Cho

doi:10.1038/nn1637

Experience-dependent modification of mechanisms of long-term depression.

J Jo, S M Ball, H Seok, S B Oh, Peter V Massey, E Molnar, Z I Bashir, K Cho

Department of Life Sciences

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46 Citations (SciVal)

Abstract

Mechanisms of long-term potentiation and depression (LTP and LTD) change considerably during development, but the importance of these changes and the factors that control them is not clear. We found that visual experience triggered a switch in mechanisms of LTD in rat perirhinal cortex, an area critical for visual recognition memory. Thus, changes in synaptic plasticity mechanisms were correlated with the changing physiological demands on the CNS.

Original language	English
Pages (from-to)	170-172
Number of pages	3
Journal	Nature Neuroscience
Volume	9
DOIs	https://doi.org/10.1038/nn1637
Publication status	Published - 2006

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title = "Experience-dependent modification of mechanisms of long-term depression.",

abstract = "Mechanisms of long-term potentiation and depression (LTP and LTD) change considerably during development, but the importance of these changes and the factors that control them is not clear. We found that visual experience triggered a switch in mechanisms of LTD in rat perirhinal cortex, an area critical for visual recognition memory. Thus, changes in synaptic plasticity mechanisms were correlated with the changing physiological demands on the CNS.",

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AU - Molnar, E

AU - Bashir, Z I

AU - Cho, K

PY - 2006

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AB - Mechanisms of long-term potentiation and depression (LTP and LTD) change considerably during development, but the importance of these changes and the factors that control them is not clear. We found that visual experience triggered a switch in mechanisms of LTD in rat perirhinal cortex, an area critical for visual recognition memory. Thus, changes in synaptic plasticity mechanisms were correlated with the changing physiological demands on the CNS.

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UR - https://www.scopus.com/pages/publications/31544451283

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M3 - Article

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SP - 170

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JO - Nature Neuroscience

JF - Nature Neuroscience

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Experience-dependent modification of mechanisms of long-term depression.

Abstract

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