Experience-dependent modification of mechanisms of long-term depression.

J Jo, S M Ball, H Seok, S B Oh, Peter V Massey, E Molnar, Z I Bashir, K Cho

Research output: Contribution to journalArticlepeer-review

45 Citations (SciVal)


Mechanisms of long-term potentiation and depression (LTP and LTD) change considerably during development, but the importance of these changes and the factors that control them is not clear. We found that visual experience triggered a switch in mechanisms of LTD in rat perirhinal cortex, an area critical for visual recognition memory. Thus, changes in synaptic plasticity mechanisms were correlated with the changing physiological demands on the CNS.
Original languageEnglish
Pages (from-to)170-172
Number of pages3
JournalNature Neuroscience
Publication statusPublished - 2006


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