Exercise is medicine-the importance of physical activity, exercise training, cardiorespiratory fitness, and obesity in the prevention and treatment of type 2 diabetes

Carl J. Lavie, Neil Johannsen, Damon Swift, Martin Senechal , Conrad Earnest, Timothy Church, Adrian Hutber, Robert Sallis , Steven N. Blair

Research output: Contribution to journalArticlepeer-review

4 Citations (SciVal)

Abstract

Type 2 diabetes has reached epidemic proportions worldwide and is associated with increased risk for cardiovascular diseases and premature mortality. Diet and physical activity (PA)-based lifestyle interventions have been shown to prevent progression to type 2 diabetes in patients at high risk. Regular PA substantially reduces the risk for type 2 diabetes and a high level of PA is associated with a substantial reduction in type 2 diabetes risk. In addition, there is strong evidence suggesting a steep inverse relationship between both PA and cardiorespiratory fitness (CRF) and mortality in patients with type 2 diabetes. Of particular concern is the dramatic, steep increase in mortality among patients with low CRF. An important point is that obese individuals who are at least moderately fit have a lower mortality risk than those who are normal weight but unfit. A large body of evidence demonstrates that exercise improves glycemic control in type 2 diabetes; the greatest improvements are achieved with combined aerobic and resistance training. A primary goal of public health strategies is to promote PA and move patients out of the least fit, high-risk cohort by increasing PA among the least active. Any plan to deal with the global epidemic of type 2 diabetes must give major attention to low PA and how this can be reversed in the general population
Original languageEnglish
Pages (from-to)95-100
Number of pages6
JournalUS Endocrinology
Volume9
Issue number2
Publication statusPublished - 2013

Keywords

  • exercise
  • fitness
  • mortality
  • physical activity
  • type 2 diabetes

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