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Evaluating School-Based Obesity Prevention Interventions in 6- to 12-Year-Old Children: a scoping review of all reported outcomes and expert consultation

Teatske Altenburg, Lotte de Vries, Janneke Van 't Hooft, Arend van Deutekom, Tessa Roseboom, Erica van den Akker, Michael Duncan, Ulf Ekelund, John J. Reilly, Lisa Reilly, Annette Stafleu, Martyn Standage, Mai Chinapaw, Deirdra Harrington

Research output: Contribution to journalReview articlepeer-review

Abstract

Introduction: This scoping review aims to identify all outcomes reported in school-based obesity prevention interventions in childhood. It serves as an essential first step towards developing an internationally agreed-upon Core Outcome Set (COS), which defines what should be measured in all school-based childhood obesity prevention studies, thereby reducing research waste and enhancing the comparability and relevance of future research. Methods: Four databases (PubMed, Embase, Cochrane Database of Systematic Reviews, and PsycINFO) were searched for published studies on controlled trials of school-based overweight/obesity prevention interventions in 6- to 12-year-olds, from inception until June 2024. Two researchers independently searched for relevant articles, extracted study/intervention characteristics, and reported outcomes. Through multiple meetings and feedback rounds, an international expert panel, including researchers (n = 5), healthcare providers (n = 4; i.e., pediatrician, youth health physician, dietician, psychologist), and a health educator identified unique outcomes underlying all reported outcomes, by reflecting on what was measured irrespective of how outcomes were defined and measured. Results: In total, 262 published studies that evaluated 242 interventions were included in this review. From these studies, we extracted 642 different reported outcomes. BMI (kg/m 2) was the most frequently reported outcome (128 studies), then BMI-z (108 studies) and BMI categories (100 studies). Experts identified 69 unique outcomes from all reported outcomes. Conclusion: There is substantial heterogeneity in outcomes reported in studies evaluating school-based overweight/obesity prevention interventions in 6- to 12-year-olds, limiting a synthesis of evidence in meta-analyses. This highlights the need for a consensus-based COS to improve the comparability and relevance of evidence of childhood obesity prevention trials.

Original languageEnglish
Article number e70125
JournalObesity Reviews
Early online date12 Mar 2026
DOIs
Publication statusE-pub ahead of print - 12 Mar 2026

Data Availability Statement

The data that support the findings of this study are available in the Supporting Information of this article.

Acknowledgements

The authors would like to thank Chloë Mikelj for her contribution to the data extraction and Lieke van Houtum (LH) and Lucy Smit (LS) for their contribution to the identification of unique outcomes.

Funding

Parts of this work were supported by the Health Behaviours and Chronic Diseases (HBCD) program of the Amsterdam Public Health Research Institute (2016 and 2017), the Wellcome Trust Institutional Strategic Support Fund at the University of Leicester (2020), and by an RSE Saltire International Collaboration Award (November 2021 to October 2022).

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • children
  • core outcome set
  • obesity prevention
  • school-based program

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Public Health, Environmental and Occupational Health

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