Enzymatic hydrolysis and selective racemisation reactions of alpha-chloro esters

L Haughton, J M J Williams

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

The kinetic resolution of a-chloro esters was effected with good selectivity using CLEC (Cross-Linked Enzyme Crystals) enzymes. The selective racemisation of a-chloro esters in the presence of alpha -chloro acids enabled a successful dynamic kinetic resolution reaction to be performed.
Original languageEnglish
Pages (from-to)943-946
Number of pages4
JournalSynthesis
Issue number6
Publication statusPublished - 2001

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    Haughton, L., & Williams, J. M. J. (2001). Enzymatic hydrolysis and selective racemisation reactions of alpha-chloro esters. Synthesis, (6), 943-946.