Engineering stereocontrol into an aldolase-catalysed reaction

H J Lamble; M J Danson; D W Hough; S D Bull

doi:10.1039/b413255f

Engineering stereocontrol into an aldolase-catalysed reaction

H J Lamble
, M J Danson
, D W Hough
, S D Bull

Department of Life Sciences

Research output: Contribution to journal › Article › peer-review

41 Citations (SciVal)

Abstract

A novel thermostable aldolase has been developed for synthetic application, and substrate engineering has been used to induce stereocontrol into aldol reactions of this naturally-promiscuous enzyme.

Original language	English
Pages (from-to)	124-126
Number of pages	3
Journal	Chemical Communications
Volume	2005
Issue number	1
DOIs	https://doi.org/10.1039/b413255f
Publication status	Published - 2005

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ID number: ISI:000225865100034

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10.1039/b413255f

Cite this

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title = "Engineering stereocontrol into an aldolase-catalysed reaction",

abstract = "A novel thermostable aldolase has been developed for synthetic application, and substrate engineering has been used to induce stereocontrol into aldol reactions of this naturally-promiscuous enzyme.",

author = "Lamble, \{H J\} and Danson, \{M J\} and Hough, \{D W\} and Bull, \{S D\}",

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JO - Chemical Communications

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Engineering stereocontrol into an aldolase-catalysed reaction

Abstract

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METABOLIC PATHWAY PROMISCUITY: A STRUCTURAL, MECHANISTIC AN D BIOCATALYTIC INVESTIGATION

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Engineering stereocontrol into an aldolase-catalysed reaction

Abstract

Bibliographical note

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METABOLIC PATHWAY PROMISCUITY: A STRUCTURAL, MECHANISTIC AN D BIOCATALYTIC INVESTIGATION

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