Engineering stereocontrol into an aldolase-catalysed reaction

H J Lamble, M J Danson, D W Hough, S D Bull

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

A novel thermostable aldolase has been developed for synthetic application, and substrate engineering has been used to induce stereocontrol into aldol reactions of this naturally-promiscuous enzyme.
Original languageEnglish
Pages (from-to)124-126
Number of pages3
JournalChemical Communications
Volume2005
Issue number1
DOIs
Publication statusPublished - 2005

Fingerprint

Fructose-Bisphosphate Aldolase
Enzymes
Substrates
3-hydroxybutanal

Cite this

Engineering stereocontrol into an aldolase-catalysed reaction. / Lamble, H J; Danson, M J; Hough, D W; Bull, S D.

In: Chemical Communications, Vol. 2005, No. 1, 2005, p. 124-126.

Research output: Contribution to journalArticle

Lamble, H J ; Danson, M J ; Hough, D W ; Bull, S D. / Engineering stereocontrol into an aldolase-catalysed reaction. In: Chemical Communications. 2005 ; Vol. 2005, No. 1. pp. 124-126.
@article{1daef64982704a79993ec5e7016182c3,
title = "Engineering stereocontrol into an aldolase-catalysed reaction",
abstract = "A novel thermostable aldolase has been developed for synthetic application, and substrate engineering has been used to induce stereocontrol into aldol reactions of this naturally-promiscuous enzyme.",
author = "Lamble, {H J} and Danson, {M J} and Hough, {D W} and Bull, {S D}",
note = "ID number: ISI:000225865100034",
year = "2005",
doi = "10.1039/b413255f",
language = "English",
volume = "2005",
pages = "124--126",
journal = "Chemical communications (Cambridge, England)",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "1",

}

TY - JOUR

T1 - Engineering stereocontrol into an aldolase-catalysed reaction

AU - Lamble, H J

AU - Danson, M J

AU - Hough, D W

AU - Bull, S D

N1 - ID number: ISI:000225865100034

PY - 2005

Y1 - 2005

N2 - A novel thermostable aldolase has been developed for synthetic application, and substrate engineering has been used to induce stereocontrol into aldol reactions of this naturally-promiscuous enzyme.

AB - A novel thermostable aldolase has been developed for synthetic application, and substrate engineering has been used to induce stereocontrol into aldol reactions of this naturally-promiscuous enzyme.

UR - http://dx.doi.org/10.1039/b413255f

U2 - 10.1039/b413255f

DO - 10.1039/b413255f

M3 - Article

VL - 2005

SP - 124

EP - 126

JO - Chemical communications (Cambridge, England)

JF - Chemical communications (Cambridge, England)

SN - 1359-7345

IS - 1

ER -