Endocarditis Caused by Nontypeable Streptococcus pneumoniae

Stefanie S V Henriet; Jeroen D Langereis; Stephanie W Lo; Stephen Bentley; Rob J Mesman; Zina Fejzic; Laura van Niftrik; Nina M van Sorge; Heiman F L Wertheim; Marien I de Jonge; Amelieke J H Cremers

doi:10.1093/cid/ciac079

Endocarditis Caused by Nontypeable Streptococcus pneumoniae

Stefanie S V Henriet, Jeroen D Langereis, Stephanie W Lo, Stephen Bentley, Rob J Mesman, Zina Fejzic, Laura van Niftrik, Nina M van Sorge, Heiman F L Wertheim, Marien I de Jonge, Amelieke J H Cremers

Department of Life Sciences

Research output: Contribution to journal › Article › peer-review

4 Citations (SciVal)

Abstract

The Streptococcus pneumoniae capsule is regarded as indispensable in bacteremia. We report an infant with a ventricular septal defect and infective endocarditis caused by nontypeable S. pneumoniae. In-depth investigation confirmed a deficient capsule yet favored pneumococcal fitness for causing infective endocarditis, rather than a host immune disorder, as the cause of infective endocarditis in this case.

Original language	English
Pages (from-to)	719-722
Number of pages	4
Journal	Clinical Infectious Diseases
Volume	75
Issue number	4
Early online date	2 Feb 2022
DOIs	https://doi.org/10.1093/cid/ciac079
Publication status	Published - 10 Sept 2022

Bibliographical note

Keywords

Endocarditis/diagnosis
Endocarditis, Bacterial/diagnosis
Humans
Infant
Pneumococcal Infections/diagnosis
Pneumonia
Streptococcus pneumoniae

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title = "Endocarditis Caused by Nontypeable Streptococcus pneumoniae",

abstract = "The Streptococcus pneumoniae capsule is regarded as indispensable in bacteremia. We report an infant with a ventricular septal defect and infective endocarditis caused by nontypeable S. pneumoniae. In-depth investigation confirmed a deficient capsule yet favored pneumococcal fitness for causing infective endocarditis, rather than a host immune disorder, as the cause of infective endocarditis in this case.",

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AU - Henriet, Stefanie S V

AU - Langereis, Jeroen D

AU - Lo, Stephanie W

AU - Bentley, Stephen

AU - Mesman, Rob J

AU - Fejzic, Zina

AU - van Niftrik, Laura

AU - van Sorge, Nina M

AU - Wertheim, Heiman F L

AU - de Jonge, Marien I

AU - Cremers, Amelieke J H

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N2 - The Streptococcus pneumoniae capsule is regarded as indispensable in bacteremia. We report an infant with a ventricular septal defect and infective endocarditis caused by nontypeable S. pneumoniae. In-depth investigation confirmed a deficient capsule yet favored pneumococcal fitness for causing infective endocarditis, rather than a host immune disorder, as the cause of infective endocarditis in this case.

AB - The Streptococcus pneumoniae capsule is regarded as indispensable in bacteremia. We report an infant with a ventricular septal defect and infective endocarditis caused by nontypeable S. pneumoniae. In-depth investigation confirmed a deficient capsule yet favored pneumococcal fitness for causing infective endocarditis, rather than a host immune disorder, as the cause of infective endocarditis in this case.

KW - Endocarditis/diagnosis

KW - Endocarditis, Bacterial/diagnosis

KW - Humans

KW - Infant

KW - Pneumococcal Infections/diagnosis

KW - Pneumonia

KW - Streptococcus pneumoniae

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DO - 10.1093/cid/ciac079

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EP - 722

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

IS - 4

ER -

Endocarditis Caused by Nontypeable Streptococcus pneumoniae

Abstract

Bibliographical note

Keywords

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