Enantioselective palladium catalysed allylic substitution with sulfur-containing oxazoline ligands

C.G. Frost, Jonathan M J Williams

Research output: Contribution to journalArticle

Abstract

Enantiomerically pure sulfur/nitrogen ligands have been prepared in one step from amino alcohols and 2-(methylthio)benzonitrile. We have successfully employed these ligands for enantioselective palladium catalysed allylic substitution, with asymmetric induction of up to 80% ee.
Original languageEnglish
Pages (from-to)1785-1788
Number of pages4
JournalTetrahedron: Asymmetry
Volume4
Issue number8
DOIs
Publication statusPublished - Aug 1993

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