Electrochemical biosensors and nanobiosensors

Jules L. Hammond, Nello Formisano, Pedro Estrela, Sandro Carrara, J Tkac

Research output: Contribution to journalReview article

52 Citations (Scopus)
84 Downloads (Pure)

Abstract

Electrochemical techniques have great promise for low-cost, miniaturised, easy-to-use, portable devices for a wide range of applications – in particular medical diagnosis and environmental monitoring. Different techniques can be used for biosensing, with amperometric devices taking the central role due to their widespread application in glucose monitoring. In fact, glucose biosensing takes a share of around 70% of the biosensor market due to the need for diabetic patients to monitor their sugar levels several times a day, making it an appealing commercial market.
In this chapter we present the basic principles of electrochemical biosensor devices. A description of the different generations of glucose sensors is used to describe in some detail the operation of amperometric sensors and how the introduction of mediators can enhance the performance of the sensors. Electrochemical impedance spectroscopy is a technique being increasingly used in devices due to its ability to detect variations in resistance and capacitance upon binding events. Novel advances in electrochemical sensors due to the use of nanomaterials such as carbon nanotubes and graphene are presented as well as well as future directions that the field is taking.
Original languageEnglish
Pages (from-to)69-80
JournalEssays in Biochemistry
Volume60
Issue number1
DOIs
Publication statusPublished - 30 Jun 2016

Fingerprint

Biosensing Techniques
Biosensors
Amperometric sensors
Glucose sensors
Glucose
Equipment and Supplies
Electrochemical sensors
Carbon Nanotubes
Graphite
Monitoring
Electrochemical impedance spectroscopy
Nanostructured materials
Sugars
Capacitance
Electrochemical Techniques
Dielectric Spectroscopy
Nanostructures
Environmental Monitoring
Sensors
Costs

Keywords

  • Biosensor
  • Electrochemistry
  • Amperometric biosensor
  • Glucose
  • Electrochemical impedance spectroscopy
  • Chronocoulometry
  • Carbon nanotubes
  • Graphene
  • Reduced graphene oxide

Cite this

Hammond, J. L., Formisano, N., Estrela, P., Carrara, S., & Tkac, J. (2016). Electrochemical biosensors and nanobiosensors. Essays in Biochemistry, 60(1), 69-80. https://doi.org/10.1042/EBC20150008

Electrochemical biosensors and nanobiosensors. / Hammond, Jules L.; Formisano, Nello; Estrela, Pedro; Carrara, Sandro; Tkac, J.

In: Essays in Biochemistry, Vol. 60, No. 1, 30.06.2016, p. 69-80.

Research output: Contribution to journalReview article

Hammond, JL, Formisano, N, Estrela, P, Carrara, S & Tkac, J 2016, 'Electrochemical biosensors and nanobiosensors', Essays in Biochemistry, vol. 60, no. 1, pp. 69-80. https://doi.org/10.1042/EBC20150008
Hammond, Jules L. ; Formisano, Nello ; Estrela, Pedro ; Carrara, Sandro ; Tkac, J. / Electrochemical biosensors and nanobiosensors. In: Essays in Biochemistry. 2016 ; Vol. 60, No. 1. pp. 69-80.
@article{fbb59baeae224ff6bde602731fb5af4b,
title = "Electrochemical biosensors and nanobiosensors",
abstract = "Electrochemical techniques have great promise for low-cost, miniaturised, easy-to-use, portable devices for a wide range of applications – in particular medical diagnosis and environmental monitoring. Different techniques can be used for biosensing, with amperometric devices taking the central role due to their widespread application in glucose monitoring. In fact, glucose biosensing takes a share of around 70{\%} of the biosensor market due to the need for diabetic patients to monitor their sugar levels several times a day, making it an appealing commercial market.In this chapter we present the basic principles of electrochemical biosensor devices. A description of the different generations of glucose sensors is used to describe in some detail the operation of amperometric sensors and how the introduction of mediators can enhance the performance of the sensors. Electrochemical impedance spectroscopy is a technique being increasingly used in devices due to its ability to detect variations in resistance and capacitance upon binding events. Novel advances in electrochemical sensors due to the use of nanomaterials such as carbon nanotubes and graphene are presented as well as well as future directions that the field is taking.",
keywords = "Biosensor, Electrochemistry, Amperometric biosensor, Glucose, Electrochemical impedance spectroscopy, Chronocoulometry, Carbon nanotubes, Graphene, Reduced graphene oxide",
author = "Hammond, {Jules L.} and Nello Formisano and Pedro Estrela and Sandro Carrara and J Tkac",
note = "Special volume {"}Biosensor technologies for detection of biomolecules{"} (Ed: P. Estrela)",
year = "2016",
month = "6",
day = "30",
doi = "10.1042/EBC20150008",
language = "English",
volume = "60",
pages = "69--80",
journal = "Essays in Biochemistry",
issn = "0071-1365",
publisher = "Portland Press Ltd.",
number = "1",

}

TY - JOUR

T1 - Electrochemical biosensors and nanobiosensors

AU - Hammond, Jules L.

AU - Formisano, Nello

AU - Estrela, Pedro

AU - Carrara, Sandro

AU - Tkac, J

N1 - Special volume "Biosensor technologies for detection of biomolecules" (Ed: P. Estrela)

PY - 2016/6/30

Y1 - 2016/6/30

N2 - Electrochemical techniques have great promise for low-cost, miniaturised, easy-to-use, portable devices for a wide range of applications – in particular medical diagnosis and environmental monitoring. Different techniques can be used for biosensing, with amperometric devices taking the central role due to their widespread application in glucose monitoring. In fact, glucose biosensing takes a share of around 70% of the biosensor market due to the need for diabetic patients to monitor their sugar levels several times a day, making it an appealing commercial market.In this chapter we present the basic principles of electrochemical biosensor devices. A description of the different generations of glucose sensors is used to describe in some detail the operation of amperometric sensors and how the introduction of mediators can enhance the performance of the sensors. Electrochemical impedance spectroscopy is a technique being increasingly used in devices due to its ability to detect variations in resistance and capacitance upon binding events. Novel advances in electrochemical sensors due to the use of nanomaterials such as carbon nanotubes and graphene are presented as well as well as future directions that the field is taking.

AB - Electrochemical techniques have great promise for low-cost, miniaturised, easy-to-use, portable devices for a wide range of applications – in particular medical diagnosis and environmental monitoring. Different techniques can be used for biosensing, with amperometric devices taking the central role due to their widespread application in glucose monitoring. In fact, glucose biosensing takes a share of around 70% of the biosensor market due to the need for diabetic patients to monitor their sugar levels several times a day, making it an appealing commercial market.In this chapter we present the basic principles of electrochemical biosensor devices. A description of the different generations of glucose sensors is used to describe in some detail the operation of amperometric sensors and how the introduction of mediators can enhance the performance of the sensors. Electrochemical impedance spectroscopy is a technique being increasingly used in devices due to its ability to detect variations in resistance and capacitance upon binding events. Novel advances in electrochemical sensors due to the use of nanomaterials such as carbon nanotubes and graphene are presented as well as well as future directions that the field is taking.

KW - Biosensor

KW - Electrochemistry

KW - Amperometric biosensor

KW - Glucose

KW - Electrochemical impedance spectroscopy

KW - Chronocoulometry

KW - Carbon nanotubes

KW - Graphene

KW - Reduced graphene oxide

UR - http://dx.doi.org/10.1042/EBC20150008

U2 - 10.1042/EBC20150008

DO - 10.1042/EBC20150008

M3 - Review article

VL - 60

SP - 69

EP - 80

JO - Essays in Biochemistry

JF - Essays in Biochemistry

SN - 0071-1365

IS - 1

ER -