Efficient rhodium and iridium-catalysed asymmetric transfer hydrogenation using water-soluble aminosulfonamide ligands

T Thorpe, J Blacker, S M Brown, C Bubert, J Crosby, S Fitzjohn, J P Muxworthy, J M J Williams

Research output: Contribution to journalArticlepeer-review

112 Citations (Scopus)

Abstract

A range of aromatic ketones was reduced asymmetrically under transfer hydrogenation conditions using enantiomerically pure catalysts derived from water-soluble diamine ligands and [Cp*MCl2](2) (Cp* = pentamethylcyclopentadienyl, M = Rh, Ir). High catalytic activity and enantioselectivity were observed in systems containing up to 51% water. (C) 2001 Elsevier Science Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)4041-4043
Number of pages3
JournalTetrahedron Letters
Volume42
Issue number24
Publication statusPublished - 2001

Fingerprint Dive into the research topics of 'Efficient rhodium and iridium-catalysed asymmetric transfer hydrogenation using water-soluble aminosulfonamide ligands'. Together they form a unique fingerprint.

Cite this