Effects of microwave-assisted extraction parameters on the recovery yield and total phenolic content of vernonia amygdalina leaf extracts with different methods of drying

Oluwaseun Ruth Alara, Nour Hamid Abdurahman, Siti Kholijah Abdul Mudalip, Olusegun Abayomi Olalere

Research output: Contribution to journalArticlepeer-review

4 Citations (SciVal)

Abstract

Vernonia amygdalina leaf has a significant importance in food and traditional medicine. It has been reported to possess various pharmacological effects. This study was carried out to investigate the influence of microwave-assisted extraction factors on the extraction from V. amygdalina leaves. The results highlighted that an increase in temperature deteriorated the yields of V. amygdalina leaf. Thus, shade-dried samples gave the highest yields at the irradiation times of 10 and 2 min, microwave power of 500 and 600 W, the temperature of 100 and 80°C, the feed-to-solvent ratio of 1:10, and ethanol concentration of 60% v/v using water and ethanol as the extracting solvents, respectively. Likewise, the antioxidant assay resulted in IC50 values of 260±1.1 ?g/mL DPPH and 149.78±0.81?g/mL ABTS for water and 204±0.92?g/mL DPPH and 31.17±1.4?g/mL ABTS for ethanol. Therefore, the synergistic mechanism of mass and heat transfer may be accounted for the accelerated extraction due to microwave energy.

Original languageEnglish
Article numbere57620
JournalJundishapur Journal of Natural Pharmaceutical Products
Volume14
Issue number1
Early online date9 Dec 2018
DOIs
Publication statusE-pub ahead of print - 9 Dec 2018

Keywords

  • Antioxidant
  • Drying
  • Extraction
  • Vernonia amygdalina
  • Yield

ASJC Scopus subject areas

  • Pharmacology, Toxicology and Pharmaceutics(all)

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