Early Language Profiles in Infants at High-Risk for Autism Spectrum Disorders

Kristelle Hudry, Susie Chandler, Rachael Bedford, Greg Pasco, Teodora Gliga, Mayada Elsabbagh, Mark H. Johnson, Tony Charman

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44 Citations (Scopus)


Many preschoolers with autism spectrum disorders (ASD) present relative lack of receptive advantage over concurrent expressive language. Such profile emergence was investigated longitudinally in 54 infants at high-risk (HR) for ASD and 50 low-risk controls, with three language measures taken across four visits (around 7, 14, 24, 38 months). HR infants presented three outcome subgroups: ASD, other atypicality, and typical development. Reduced receptive vocabulary advantage was observed in HR infants by 14 months, but was maintained to 24 months only in ASD/other atypicality outcome subgroups while typically-developing HR infants regained a more normative profile. Few group differences appeared on a direct assessment of language and parent-reported functional communication. Processes of early development toward ASD outcome and in intermediate phenotypes are discussed.
Original languageEnglish
Pages (from-to)154-167
Number of pages14
JournalJournal of Autism and Developmental Disorders
Issue number1
Early online date8 Jun 2013
Publication statusPublished - 31 Jan 2014


  • Autism spectrum disorder
  • Broader autism phenotype
  • High-risk siblings
  • Receptive language
  • Expressive language
  • Language profiles

Cite this

Hudry, K., Chandler, S., Bedford, R., Pasco, G., Gliga, T., Elsabbagh, M., Johnson, M. H., & Charman, T. (2014). Early Language Profiles in Infants at High-Risk for Autism Spectrum Disorders. Journal of Autism and Developmental Disorders, 44(1), 154-167. https://doi.org/10.1007/s10803-013-1861-4