Early Language Profiles in Infants at High-Risk for Autism Spectrum Disorders

Kristelle Hudry, Susie Chandler, Rachael Bedford, Greg Pasco, Teodora Gliga, Mayada Elsabbagh, Mark H. Johnson, Tony Charman

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

Many preschoolers with autism spectrum disorders (ASD) present relative lack of receptive advantage over concurrent expressive language. Such profile emergence was investigated longitudinally in 54 infants at high-risk (HR) for ASD and 50 low-risk controls, with three language measures taken across four visits (around 7, 14, 24, 38 months). HR infants presented three outcome subgroups: ASD, other atypicality, and typical development. Reduced receptive vocabulary advantage was observed in HR infants by 14 months, but was maintained to 24 months only in ASD/other atypicality outcome subgroups while typically-developing HR infants regained a more normative profile. Few group differences appeared on a direct assessment of language and parent-reported functional communication. Processes of early development toward ASD outcome and in intermediate phenotypes are discussed.
Original languageEnglish
Pages (from-to)154-167
Number of pages14
JournalJournal of Autism and Developmental Disorders
Volume44
Issue number1
Early online date8 Jun 2013
DOIs
Publication statusPublished - 31 Jan 2014

Keywords

  • Autism spectrum disorder
  • Broader autism phenotype
  • High-risk siblings
  • Receptive language
  • Expressive language
  • Language profiles
  • COMMUNICATIVE DEVELOPMENT
  • CHILDREN
  • PRESCHOOLERS
  • IMPAIRMENT
  • VOCABULARY
  • ABILITIES
  • TODDLERS

Cite this

Hudry, K., Chandler, S., Bedford, R., Pasco, G., Gliga, T., Elsabbagh, M., Johnson, M. H., & Charman, T. (2014). Early Language Profiles in Infants at High-Risk for Autism Spectrum Disorders. Journal of Autism and Developmental Disorders, 44(1), 154-167. https://doi.org/10.1007/s10803-013-1861-4