Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRas Q61L)-driven SerpinB2 expression

Linda K. Rushworth, Andrew M. Kidger, Laurent Delavaine, Graeme Stewart, Susanne Van Schelven, Jane Davidson, Christopher J. Bryant, Edward Caddye, Philip East, Christopher J. Caunt, Stephen M. Keyse

Research output: Contribution to journalArticlepeer-review

59 Citations (SciVal)
Original languageEnglish
Pages (from-to)18267-18272
Number of pages6
JournalProceedings of the National Academy of Sciences of the United States of America
Issue number51
Early online date8 Dec 2014
Publication statusPublished - 23 Dec 2014


  • DUSP5
  • MAP Kinase
  • Protein phosphatases
  • SerpinB2
  • Skin cancer

Cite this