Dual selective iron chelating probes for the monitoring of mitochondrial labile iron pools

Vincenzo Abbate, Olivier Reelfs, Xiaole Kong, Charareh Pourzand, Robert C Hider

Research output: Contribution to journalArticlepeer-review

23 Citations (SciVal)
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Abstract

Mitochondria-targeted peptides incorporating dual fluorescent and selective iron chelators have been designed as novel biosensors for the mitochondrial labile iron pool. The probes were demonstrated to specifically co-localize with mitochondria and their fluorescence emission was found to be sensitive to the presence of iron.
Original languageEnglish
Pages (from-to)784-787
Number of pages4
JournalChemical Communications
Volume52
Issue number4
Early online date9 Nov 2015
DOIs
Publication statusPublished - 14 Jan 2016

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