Drosophila melanogaster embryonic haemocytes: masters of multitasking

William Wood, Antonio Jacinto

Research output: Contribution to journalArticle

129 Citations (Scopus)

Abstract

Drosophila melanogaster haemocytes constitute the cellular arm of a robust innate immune system in flies. In the adult and larva, these cells operate as the first line of defence against invading microorganisms: they phagocytose pathogens and produce antimicrobial peptides. However, in the sterile environment of the embryo, these important immune functions are largely redundant. Instead, throughout development, embryonic haemocytes are occupied with other tasks: they undergo complex migrations and carry out several non-immune functions that are crucial for successful embryogenesis.
Original languageEnglish
Pages (from-to)542-551
Number of pages10
JournalNature Reviews Molecular Cell Biology
Volume8
Issue number7
DOIs
Publication statusPublished - Jul 2007

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