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Draft genome sequence of endometrial Alloscardovia omnicolens strain Y28 identified in endometrial cancer

Gwenllian A. Anwyl, Nicole R. Jimenez , Bonnie Hurwitz , Melissa M. Herbst-Kralovetz

Research output: Contribution to journalArticlepeer-review

Abstract

We report a 1.8 Mb draft genome of Alloscardovia omnicolens Y28 isolated from a patient with endometrial cancer.
Original languageEnglish
Number of pages5
JournalMicrobiology Resource Announcements
Volume15
Issue number3
Early online date10 Feb 2026
DOIs
Publication statusPublished - 31 Mar 2026

Data Availability Statement

The draft genome sequence of A. omnicolens Y28 has been deposited at the Sequence Read Archive (SRA) under accession number NZ_JBRAVA000000000. This genome is part of a larger BioProject PRJNA1354867. The genome BioSample identification is SAMN51299389. The genome annotation can also be found at GenBank GCF_052772085.1, and additional genome assembly, annotation, protein family, and phylogenetic analysis information are available at BV-BRC (https://www.bv-brc.org/workspace/[email protected]/Alloscardovia) with access via a free account. Additional assembly information and parameters utilized can be found at https://github.com/hurwitzlab/vaginal_genome_assembly.

Funding

This study received primary support from the Mary Kay Foundation Translational Research Grant awarded to M.M.H-K. We extend our gratitude to the patient who participated in the parent study, as well as the clinical team and research coordinators for their invaluable assistance with patient recruitment, sample collection, and clinical data gathering. We also acknowledge Dr. Pawel Laniewski for providing additional support for bacterial cultivation, including funding from the Arizona Biomedical Research Center New Investigator Award (RFGA2022-010-05). Additional funding was provided by the University of Arizona Health Sciences Strategic Plan Initiative 4.1. Personalized Defense. The American Cancer Society Postdoctoral Fellowship, PF-24-1316926-01-MM, supported N.R.J.'s work on the endometrial microbiome. N.R.J. is part of the Guiding U54 Investigator Development to Sustainability (GUIDeS) shared resource, a part of the Partnership for Native American Cancer Prevention, which is funded under parallel grants, U54CA143924 and U54CA143925, and supports early-stage investigators.

FundersFunder number
Mary Kay Ash Foundation
University of Arizona
Arizona Biomedical Research CenterRFGA2022-010-05
American Cancer SocietyPF-24-1316926-01-MM, U54CA143924, U54CA143925

    UN SDGs

    This output contributes to the following UN Sustainable Development Goals (SDGs)

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being

    Keywords

    • human microbiome
    • Alloscardovia omnicolens
    • endometrial cancer
    • gynecologic health
    • endometrial microbiota

    ASJC Scopus subject areas

    • Molecular Biology
    • Immunology and Microbiology (miscellaneous)
    • Genetics

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