Does highly cross-linked polyethylene wear less than conventional polyethylene in total hip arthroplasty? A double-blind, randomized, and controlled trial using roentgen stereophotogrammetric analysis

S. Glyn-Jones, S. Isaac, J. Hauptfleisch, P. McLardy-Smith, D. W. Murray, H. S. Gill

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Abstract

A prospective double-blind, randomized, and controlled trial was conducted using roentgen stereophotogrammetric analysis; 54 total hip arthroplasty patients were randomized to receive either highly cross-linked polyethylene (HXLPE) or standard ultra-high-molecular-weight polyethylene (UHMWPE) liners. The 3-dimensional penetration of the liner was determined over 2 years. For the first 3 months, both polyethylene types had a rapid penetration rate (HXLPE: 0.22 mm, SD = 0.17 mm; UHMWPE: 0.21 mm, SD = 0.15 mm; P = .78). After 3 months, the HXLPE penetration rate (0.06 mm/y, SD = 0.06 mm/y) was significantly lower than the UHMWPE penetration rate (0.10 mm/y, SD = 0.07 mm/y; P = .04). The penetration in the first 3 months was probably caused by creep or bedding in; from 3 months onward, much of the penetration was probably caused by wear. We conclude that HXLPE has a 40% lower wear rate as compared with UHMWPE, suggesting that it will perform better in the long term.
Original languageEnglish
Pages (from-to)337-343
Number of pages7
JournalJournal of Arthroplasty
Volume23
Issue number3
DOIs
Publication statusPublished - 2008

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Polyethylene
Arthroplasty
Hip
Randomized Controlled Trials
ultra-high molecular weight polyethylene

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Does highly cross-linked polyethylene wear less than conventional polyethylene in total hip arthroplasty? A double-blind, randomized, and controlled trial using roentgen stereophotogrammetric analysis. / Glyn-Jones, S.; Isaac, S.; Hauptfleisch, J.; McLardy-Smith, P.; Murray, D. W.; Gill, H. S.

In: Journal of Arthroplasty, Vol. 23, No. 3, 2008, p. 337-343.

Research output: Contribution to journalArticle

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abstract = "A prospective double-blind, randomized, and controlled trial was conducted using roentgen stereophotogrammetric analysis; 54 total hip arthroplasty patients were randomized to receive either highly cross-linked polyethylene (HXLPE) or standard ultra-high-molecular-weight polyethylene (UHMWPE) liners. The 3-dimensional penetration of the liner was determined over 2 years. For the first 3 months, both polyethylene types had a rapid penetration rate (HXLPE: 0.22 mm, SD = 0.17 mm; UHMWPE: 0.21 mm, SD = 0.15 mm; P = .78). After 3 months, the HXLPE penetration rate (0.06 mm/y, SD = 0.06 mm/y) was significantly lower than the UHMWPE penetration rate (0.10 mm/y, SD = 0.07 mm/y; P = .04). The penetration in the first 3 months was probably caused by creep or bedding in; from 3 months onward, much of the penetration was probably caused by wear. We conclude that HXLPE has a 40{\%} lower wear rate as compared with UHMWPE, suggesting that it will perform better in the long term.",
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