Directed self-assembly of dipeptides to form ultrathin hydrogel membranes

Eleanor K Johnson, D J Adams, Petra J Cameron

Research output: Contribution to journalArticlepeer-review

111 Citations (SciVal)


The dipeptide amphiphile Fmoc-Leu-Gly-OH has been induced to self-assemble into thin surface-supported hydrogel gel films and gap-spanning hydrogel membranes. The thickness can be closely controlled, giving films/membranes from tens of nanometers to millimeters thick. SEM and TEM have confirmed that the dipeptides self-assemble to form fibers, with the membranes resembling a dense "mat" of entangled fibers. The films and membranes were stable once formed. The films could be reversibly dried and collapsed, then reswollen to regain the gel structure.
Original languageEnglish
Pages (from-to)5130-5136
Number of pages7
JournalJournal of the American Chemical Society
Issue number14
Early online date22 Mar 2010
Publication statusPublished - 14 Apr 2010


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