Directed self-assembly of dipeptides to form ultrathin hydrogel membranes

Eleanor K Johnson; D J Adams; Petra J Cameron

doi:10.1021/ja909579p

Directed self-assembly of dipeptides to form ultrathin hydrogel membranes

Eleanor K Johnson, D J Adams, Petra J Cameron

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

112 Citations (SciVal)

Abstract

The dipeptide amphiphile Fmoc-Leu-Gly-OH has been induced to self-assemble into thin surface-supported hydrogel gel films and gap-spanning hydrogel membranes. The thickness can be closely controlled, giving films/membranes from tens of nanometers to millimeters thick. SEM and TEM have confirmed that the dipeptides self-assemble to form fibers, with the membranes resembling a dense "mat" of entangled fibers. The films and membranes were stable once formed. The films could be reversibly dried and collapsed, then reswollen to regain the gel structure.

Original language	English
Pages (from-to)	5130-5136
Number of pages	7
Journal	Journal of the American Chemical Society
Volume	132
Issue number	14
Early online date	22 Mar 2010
DOIs	https://doi.org/10.1021/ja909579p
Publication status	Published - 14 Apr 2010

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10.1021/ja909579p

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Directed self-assembly of dipeptides to form ultrathin hydrogel membranes

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Hybrid Materials for Enzymatic Reductions of Carbon Dioxide

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Directed self-assembly of dipeptides to form ultrathin hydrogel membranes

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