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The dipeptide amphiphile Fmoc-Leu-Gly-OH has been induced to self-assemble into thin surface-supported hydrogel gel films and gap-spanning hydrogel membranes. The thickness can be closely controlled, giving films/membranes from tens of nanometers to millimeters thick. SEM and TEM have confirmed that the dipeptides self-assemble to form fibers, with the membranes resembling a dense "mat" of entangled fibers. The films and membranes were stable once formed. The films could be reversibly dried and collapsed, then reswollen to regain the gel structure.
Johnson, E. K., Adams, D. J., & Cameron, P. J. (2010). Directed self-assembly of dipeptides to form ultrathin hydrogel membranes. Journal of the American Chemical Society, 132(14), 5130-5136. https://doi.org/10.1021/ja909579p