Directed self-assembly of dipeptides to form ultrathin hydrogel membranes

Eleanor K Johnson, D J Adams, Petra J Cameron

Research output: Contribution to journalArticle

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Abstract

The dipeptide amphiphile Fmoc-Leu-Gly-OH has been induced to self-assemble into thin surface-supported hydrogel gel films and gap-spanning hydrogel membranes. The thickness can be closely controlled, giving films/membranes from tens of nanometers to millimeters thick. SEM and TEM have confirmed that the dipeptides self-assemble to form fibers, with the membranes resembling a dense "mat" of entangled fibers. The films and membranes were stable once formed. The films could be reversibly dried and collapsed, then reswollen to regain the gel structure.
LanguageEnglish
Pages5130-5136
Number of pages7
JournalJournal of the American Chemical Society
Volume132
Issue number14
Early online date22 Mar 2010
DOIs
StatusPublished - 14 Apr 2010

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Dipeptides
Hydrogel
Hydrogels
Self assembly
Membranes
Gels
Regain
Amphiphiles
Fibers
Transmission electron microscopy
Scanning electron microscopy

Cite this

Directed self-assembly of dipeptides to form ultrathin hydrogel membranes. / Johnson, Eleanor K; Adams, D J; Cameron, Petra J.

In: Journal of the American Chemical Society, Vol. 132, No. 14, 14.04.2010, p. 5130-5136.

Research output: Contribution to journalArticle

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