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The direct coupling of unactivated carboxylic acids with amines can be performed in toluene 110 degrees C in the absence of catalyst. The use of simple zirconium catalysts at 5 mol% loading gave amide formation in as little as 4 h.
|Number of pages||3|
|Publication status||Published - 2012|
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- 1 Finished
Engineering and Physical Sciences Research Council
1/08/11 → 10/05/13
Project: Research council