Development of metal complexes as potential antimicrobials

Albert Bolhuis; Adair D Richards

doi:10.1007/978-3-211-99079-7_15

Development of metal complexes as potential antimicrobials

Albert Bolhuis, Adair D Richards

Department of Life Sciences

Research output: Chapter or section in a book/report/conference proceeding › Book chapter

Abstract

In 1969, the Surgeon General of the USA said that it was time “to close the book on infectious diseases” on the basis of the prolific success of antibiotics in the previous quarter century that had been widely prescribed [1]. This optimism, whilst seemingly justified at the time, was seriously misjudged, as the intervening 40 years have clearly demonstrated. This is because of the previously disregarded ability of bacteria to genetically mutate to an extent where future generations of bacteria proved immune to the effects of specific antibiotics – hence the need for novel approaches to combating microbial infections is as great as ever.

Original language	English
Title of host publication	Metallointercalators: Synthesis and Techniques to Probe Their Interactions with Biomolecules
Editors	J Aldrich-Wright
Place of Publication	New York
Publisher	Springer
Pages	373-388
Number of pages	16
ISBN (Print)	978-3-211-09427-3
DOIs	https://doi.org/10.1007/978-3-211-99079-7_15
Publication status	Published - 2011

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10.1007/978-3-211-99079-7_15

Cite this

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ER -

Development of metal complexes as potential antimicrobials

Abstract

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